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Chinese Journal of Joint Surgery(Electronic Edition) ›› 2025, Vol. 19 ›› Issue (02): 236-242. doi: 10.3877/ cma.j.issn.1674-134X.2025.02.014

• REVIEWS • Previous Articles    

Research progress on influencing factors of early mobilization after total knee arthroplasty

Junjie Chen1, Ming Qu2, Jinyu Zhu3,()   

  1. 1. Zhejiang Chinese Medical University, Hangzhou310053, China
    2. Department of Orthopaedics, Fuping County Hospital, Shanxi 711700, China
    3. Department of Orthopaedics, The Affiliated Hospital of Jiaxing University & The First Hospital of Jiaxing, Jiaxing 314001, China
  • Received:2024-10-14 Online:2025-04-01 Published:2025-06-17
  • Contact: Jinyu Zhu

Abstract:

Early mobilization after total knee arthroplasty is a central aspect of ERAS,and there are many factors that affect early mobilization. The safety of early mobilization is a top priority, and preventing falls is of utmost importance. This article reviewed the research progresses on influencing factors including general conditions, nutrition, pre-rehabilitation, postoperative pain management, surgical approach, prosthesis type,tourniquet usage, and quadriceps muscle strength on early postoperative mobilization, for clinical practice reference. The "cocktail" injection of long-acting analgesics such as ropivacaine or bupivacaine liposomes intraoperatively can provide long-lasting postoperative pain relief without affecting the function of the quadriceps muscle, which is more helpful for early mobilization. Surgeons shall try not using tourniquets during surgery or using tourniquets for a short period of time to avoid negative effects on early mobilization. The impact of quadriceps muscle strength, application of tranexamic acid, and intelligent assistive technologies such as robots, navigation on early postoperative mobilization needs further research.

Key words: Arthroplasty, replacement, knee, Early ambulation, Enhanced recovery after surgery

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